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Th?n tho?i hy l?p pdf

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Rejuvenation of aged progenitor cells by exposure to a young systemic environment. PLoS Genet. Absence of effects of Sir2 overexpression on lifespan in C. Among the downstream effectors of the IIS pathway, the most relevant one for longevity in worms and flies is the transcription factor FOXO Kenyon et al. The last criterion is the most difficult to achieve, even if restricted to just one aspect of aging. Notably, rapamycin delays multiple aspects of aging in mice Wilkinson et al. The sirtuin family of NAD-dependent protein deacetylases and ADP-ribosyltransferases has been studied extensively as potential anti-aging factors.

Pdf l?p tho?i th?n hy

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